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Animal Behavior Video Analysis Working Group
February 16 @ 3:00 pm - 5:00 pm
Title: Mapping the landscape of social of social behavior using high-resolution 3D tracking of freely interacting animals
Presenter: Ugne Klibaite, PhD
Harvard University, Department of Organismic & Evolutionary Biology (PI, Bence P. Ölveczky)
Abstract: Social interaction is a fundamental component of animal behavior. However, we lack tools to describe it with quantitative rigor, limiting our understanding of its principles and the neuropsychiatric disorders, like autism, that perturb it. To address these limitations, I and collaborators have developed a technique for high-resolution 3D tracking of freely interacting animals and their body-wide social touch patterns, solving the challenging subject occlusion and part assignment problems using 3D geometric reasoning, graph neural networks, and semi-supervised learning. Using this technology, I have collected and annotated over 34 million 3D postures in interacting rats, featuring five new monogenic autism models lacking reports of social behavioral phenotypes. I will introduce a novel multi-scale approach which I have used to identify a rich landscape of stereotyped interactions, synchrony, and body contact across strains. This deep phenotyping approach revealed a spectrum of changes in rat autism models and in response to amphetamine, and this framework has the potential to facilitate quantitative studies of social behaviors and their neurobiological underpinnings.
Join Zoom Meeting:
https://columbiauniversity.zoom.us/j/94848687512pwd=d0d2L20wSUdZWGZ4dytuZ1YyaEt3QT09
Meeting ID: 948 4868 7512
Passcode: 446335